Stampede Sunday, as I like to call it, was as packed as it
is each year.
There was lots of cool science to talk about and cool scientists
to talk about it with. Here with the highlights ---
1. Hendrix (DD56) – Her aim was to raise awareness for her
local “brain awareness day”. She was able to do by promoting via social media
and designing flyers. She also talked about having visited Capitol Hill and talking
to policy-makers about the changing funding climate. Basically, Ms. Hendrix is
an advocate for both neuroscience and neuroscientists. We need more people like
her. Follow her @RDHendrix.
2. Brager (DD38) – a fellow blogger, her poster showed that
cryotherapy increases both the amount as well as the quality of sleep in athletes. Sleep remains an
underappreciated area of neuroscience and I saw some other cool work looking at
sleep disruption in rodent models. Brager’s work was particularly fascinating because it was in
athletes; something many of us ex-athletes can appreciate. Basically - those ice baths are really, really important for recovery. And, if possible, a cryo chambers is even better.
3. Whitesall (D31) – Working at the Allen Institute, Ms.
Whitesall’s work looked at Default Mode Network (DMN) in the mouse brain. In
recent years, the idea of the Default Mode – essentially, the baseline of your
brain activity – has become apparent. It makes for both interesting science, as
well as interesting science fiction. Whitesall’s work hypothesizes that the
brain regions comprising the DMN may be one of the first to perturbed in
Alzhiemer’s Disease. She will test whether this is true in an AD transgenic mouse line.
4. Kawarabayashi – Looking at tg mice models, they found that
PrPc, Abeta mono and dimers, Fyn, NMDA, GSK3beta and pTau all localized in
lipid rafts! This ties in both the possible involvement of lipid rafts in AD,
as well as seemed to support the amyloid hypothesis.
5. Graham (C87) – Western diet in APP/PS1 mice increases A-beta
load and TREM2 activation. TREM2 is the new baby in the AD field, and there
will be a lot of work on it. And, as for western diet, STOP BEING SUCH FATTIES, YOU GUYS. And, by you, i mean, me.
6. Brkic (C86) – Omega-3-Fatty Acids have beneficial effects on
brain of AD mice – by reducing amyloid plaque burden. There was recently a
longitudinal study that determined that fish oil showed no benefit for cognition
in AD patients. Brkic informed me that she thought that study was done with
patients who has advanced AD, and therefore, an amelioration of symptoms would
have been lost in the noise of progressed neurodegeneration. I agree with her.
Most AD therapies should be looking at helping decelerate the pathology in mild
cognitive impairment patients, in my opinion.
7. Colello (C91) – This was my favorite poster of the day.
Their group decided to address the issue of the g-forces experienced by helmet
to helmet collisions in football players. They posit doing so by placing repulsive
magnets in the helmet of players. This would lead to the generation of a
repulsive force that would reduce the g-forces. Their proof of concept suggests
that they are able to reduce g-forces (measured by accelerometers) in a rig
where they are essentially crashing two helmets together. This is fascinating
work! And, a perfect example of how invention often come from people who cross
disciplines.
Lunch
All the places close by were closed! Stampede Sunday is the worst. I ate a sandwich from a grocery store. It was awful.
Afternoon sesh
I spent the entire time presenting the boss-man's poster.
What were your highlights from today? My poster is tomorrow (Afternoon session, D25). Stop by and say hi!
go to chinatown 15 minutes walk away for lunch...
ReplyDeleteThanks for the tip. Unfortunately, I didn't have time today - I had to be back to set up my poster. Any favorite restaurants in Chinatown that you would recommend?
DeleteFor a quick/cheap/filling meal, go to Joy Yee or one of the two BBQ places. The BBQ shops sells takeout lunchboxes of 2 roast meats (eg. roast duck+pork) + rice + soup for ~$7. If you have a group the Lao Szechuan/Hunan/Shanghai are pretty good.
DeleteFor those people who's relative are Alzheimer’s Disease sufferer and maybe reading this, I find it hard that people are still ignorant of herbal medicine when it comes to treating Alzheimer’s Disease.
ReplyDeleteI have been through many phases over the last couple of years since my father's diagnosis, he was 53 years old and had Early Onset Alzheimer’s Disease and his diagnosis changed my life in many ways, I spend most of the time in denial and I keep thinking the tests were wrong. But deep down I knew they were correct. Though sharing his story is very difficult. He was always very successful in being able to accomplish anything he set his mind on doing. Alzheimer’s is a bitch of a disease. It began by robbing his recent memory, but it didn't stop there. It continues to steal, taking the most recent memories until it has pilfered all but the oldest memories, he experienced a decline in his ability to think, remember and make decisions. I feel a need to express my thoughts and feelings about how it affected his day to day living and how its deteriorated since despite the help of some wonderful medics and medicine.
I remind myself how lucky to come across Charanjit rychtova's herbal medicine which is able to control this disease without any side effect, I felt a moment of relief hoping that he is free from this ailment, and nothing compares to the healing power of nature. Now I believe almost every health problem can be addressed in one natural way or another. The only thing I wanted was for him to feel better. I’m proud to say my Dad is Alzheimer’s free. You can also contact him for more info. at charantova@gmail.com
In my own case it was just over four years ago when my Mum began to sound different on the phone. She lived back East with my siblings and my husband and I were living on the West coast and in phone calls it became apparent that my Mum's voice no longer had the same tones of excitement and humor that she used to; and instead it was very flat. At the same time she began to tell us about a situation at work that just didn't seem possible; she was complaining that a group of fellow workers were conspiring to get her. Although Mum had much academic success as a teenager, her behavior had become increasingly odd during the past years. She quit seeing her friends and no longer seemed to care about her appearance or social pursuits. She began wearing the same clothes each day and seldom bathed. She lived with several family members but rarely spoke to any of us. Obviously this whole story seemed very unbelievable and we sensed something was wrong but had no clue as to what it could be. We recommended that my Mum quit her job and look for something else - as we began to wonder if she had a "mental breakdown" and would get better once out of the stressful job situation.
ReplyDeleteIn the case of Mum, she was having persecurtory delusions, auditory hallucinations and negative symptoms that had lasted for at least Three years. All of these symptoms fit with a diagnosis of Dementia. Her story reflects a common case, in which a high-functioning young adult goes through a major decline in day-to-day skills. Although family and friends may feel this is a loss of the person they knew, the illness can be treated and a good outcome is possible as it all got better when we started using a herbal medicine for her through Aparajita.
My recommendation to people who are either wondering if they have DEmentia or wondering if a friend or loved one has Dementia should contact aparajitatan@gmail.com. I think one of our key problems was that we didn't do this in the early days of my Mum's illness as we never thought of a natural alternative for her.
In my own case it was just over four years ago when my Mum began to sound different on the phone. She lived back East with my siblings and my husband and I were living on the West coast and in phone calls it became apparent that my Mum's voice no longer had the same tones of excitement and humor that she used to; and instead it was very flat. At the same time she began to tell us about a situation at work that just didn't seem possible; she was complaining that a group of fellow workers were conspiring to get her. Although Mum had much academic success as a teenager, her behavior had become increasingly odd during the past years. She quit seeing her friends and no longer seemed to care about her appearance or social pursuits. She began wearing the same clothes each day and seldom bathed. She lived with several family members but rarely spoke to any of us. Obviously this whole story seemed very unbelievable and we sensed something was wrong but had no clue as to what it could be. We recommended that my Mum quit her job and look for something else - as we began to wonder if she had a "mental breakdown" and would get better once out of the stressful job situation.
ReplyDeleteIn the case of Mum, she was having persecurtory delusions, auditory hallucinations and negative symptoms that had lasted for at least Three years. All of these symptoms fit with a diagnosis of Dementia. Her story reflects a common case, in which a high-functioning young adult goes through a major decline in day-to-day skills. Although family and friends may feel this is a loss of the person they knew, the illness can be treated and a good outcome is possible as it all got better when we started using a herbal medicine for her through Aparajita.
My recommendation to people who are either wondering if they have DEmentia or wondering if a friend or loved one has Dementia should contact aparajitatan@gmail.com. I think one of our key problems was that we didn't do this in the early days of my Mum's illness as we never thought of a natural alternative for her.
As a sign of gratitude for how my son was saved from dementia , i decided to reach out to those still suffering from this.
ReplyDeleteMy son suffered dementia and it was really tough and heartbreaking for me because he was my all and the symptoms were terrible, we tried various therapies prescribed by our neurologist but none could cure him. I searched for a cure and i saw a testimony of so many people who was cured from dementia and so many other with similar body problem, and they left the contact of the doctor who had the herbal cure to dementia . I never imagined dementia has a cure not until i contacted him and he assured me my son will be fine. I got the herbal medication he recommended and my son used it and in one months he was fully okay even up till this moment he is so full of life. dementia has a cure and it is a herbal cure contact the doctor for more info on drwilliams098675@gmail.com on how to get the medication. Thanks for reading my testimony
I can’t forget in a hurry my Mom's horrible years of fight with Mental ailment (Alzheimer). My Mom got really sick around Christmas that year. When I saw her in the hospital with all those tubes, I just lost it. I got so hysterical that I had to be escorted out. Soon after that, I got into that altercation with my neighbor and was sent to jail. When I got out of jail, Her symptoms were acting up and I felt so angry. Dad had already taken her to a state psychiatric hospital. I was really nervous, but I talked to a psychiatrist there who made me feel comfortable. For the first time, she opened up about what she was experiencing—the voices, not being able to remember things, the paranoia. She said, “Your mom is battling Alzheimer.” I didn’t even know what that meant.
ReplyDeleteHe suggested that when she got out of the hospital and off the treatments she was taking there, we try a new treatment for Alzheimer. After weighing the risks and benefits, we both agreed the treatment, given through monthly injections, might help control her symptoms. Meanwhile, I made friends, and gained insight into her illness. During the week, there were movies, cooking classes and education sessions about her disease—basically, activities to help people like her get back into society. I learned about Alzheimer and what some of her triggers were. All told, she stayed there for two months and we left, I was taking her for doctor’s appointments and grocery shopping. It was hard, especially when her birthday passed, I still helped her walk, fix her food and dress her which made me sad because she was very active at 69 until the illness struck her.
I came across a herbal medication sometimes last year called zomo but before we started the treatment, we started a day rehabilitation program, and also started the new medication with zomo. I was working hard to achieve my care goals by following the treatment plan. Her symptoms got under control within three months, as she started feeling better. First she regained interest in the things she used to enjoy, like calling/visiting our family and friends for lunch and going for walks in the park and grocery shopping. I will never forget what I went through, or what it took for her to get here. I don’t take any of it for granted. I consider myself an advocate for people who don’t have any knowledge about this herbal medicine. To anyone who’s taken the time to read this that may be struggling with this awful ailment (Alzheimer), reach out, share, I guarantee you reach out to charantova@gmail.com, and know, that as lonely as you may feel, as hopeless as you believe things are, please know, that there are so many patients out there going through same and you are never alone! reach out to him so you could share your own testimony to let others know there is hope.